United States securities and exchange commission logo

                           October 8, 2020

       Alfred Altomari
       Chairman and Chief Executive Officer
       Agile Therapeutics, Inc.
       101 Poor Farm Road
       Princeton, NJ 08540

                                                        Re: Agile Therapeutics,
Statement on Form S-3
                                                            Filed October 2,
                                                            File No. 333-249273

       Dear Mr. Altomari:

              This is to advise you that we have not reviewed and will not
review your registration

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jason L.
Drory at 202-551-8342 with any questions.


                           Division of Corporation Finance

                           Office of Life Sciences
       cc:                                              Bryan S. Keighery, Esq.