United States securities and exchange commission logo April 19, 2023 Alfred Altomari Chief Executive Officer Agile Therapeutics, Inc. 500 College Road East, Suite 310 Princeton, NJ 08540 Re: Agile Therapeutics, Inc. Registration Statement on Form S-1 Filed April 14, 2023 File No. 333-271249 Dear Alfred Altomari: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Jason Drory at 202-551-8342 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Bryan S. Keighery